Health Cluster Portugal (HCP) Membership Directory

Instituto de Biologia Molecular e Celular - IBMC

http://www.ibmc.up.pt/

Category(ies): Academic Institutions; R&D Institutions

Subcluster(s):

Address: Rua do Campo Alegre, 823; 4150-180 Porto; Portugal

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Keyword(s): Cell Biology, Immunity, Infection, Neurobiology, Structural Biology

IBMC is part of the i3S Research Unit, recently evaluated by the FCT and classified as "Exceptional". i3S is a multidisciplinary institution with the mission of promoting research and innovation in the Health Sciences at the highest international level, carry out graduate training and contribute to solve current social challenges in the areas of Cancer, Neurobiology and Host Interaction and Response. IBMC is organized in three thematic units: Infection and Immunity, Neuroscience and Molecular and Cell Biology, with 49 research groups and over 200 researchers that pursue more than 100 projects funded nationally or internationally. We host researchers funded by various sources and Lecturers from faculties of the University of Porto. IBMC supports graduate training in PhD programs and currently host 220 PhD students. We explore technology transfer and industry contract research demonstrating our commitment for the translation of research into value for society. We have a policy of share core scientific services, including Light and Electron Microscopy, Protein Production and Purification, Cell Culture and Genotyping, Flow Cytometry, Analytical Biochemistry, High-Throughput screening and Animal Facility. Given the social implications and public interest our work, we actively encouraged our researchers to engage in public activities such as school talks and projects, science fairs and other public events and science-media cooperation. (www.ibmc.up.pt and www.i3s.up.pt)

R&D Projects

A role for Nrf2/ARE cytoprotective signalling in iron overload. Adaptive response to oxidative stress as a disease modifier in HFE associated hereditary hemochromatosis

Application of combined bioinformatic and experimental approaches to elucidate a clinical preeclamsia management strategy

Characterization of cell-intrinsic axonal regeneration determinants and their use to promote repair after CNS injury

Endocannabinoids as lipid mediators in reproduction

Genetic predisposition versus the effect of regular physical exercise on circulating adipokine levels in obese Portuguese adolescents

Metal (iron and zinc) metabolism in Leishmania

New enzyme inhibitors for breast and prostate cancers: insights to overcome bone loss and endocrine resistance

Pre-clinical assays of a GAPDH-based vaccine against Group B Streptococcus infection

Role of the yeast neutral sphingomyelinase in mitochondria function and iron homeostasis

Significance of the Leishmania infantum mitochondrial 2-cysteine peroxiredoxin chaperone activity and its role in parasite infectivity

Study of the immune response and protective effect against neosporosis elicited by mucosal immunization with Neospora caninum antigens